en <span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong><span style="font-size:10.0pt"><span style="font-family:"Cambria",serif"><span style="color:#44546a">Aims:</span></span></span></strong><span style="font-size:10.0pt"><span style="font-family:"Cambria",serif"> Intravenous cannulation is a common invasive procedure that causes pain, anxiety and technical challenges in both adults and children. This study evaluated nurses’ Intravenous cannulation skills and related influencing factors at Kashan University of Medical Sciences hospitals.</span></span></span></span><br> <span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong><span style="font-size:10.0pt"><span style="font-family:"Cambria",serif"><span style="color:#44546a">Instrument & Methods:</span></span></span></strong> <span style="font-size:10.0pt"><span style="font-family:"Cambria",serif">In this descriptive observational study, which is conducted in 2024 in Kashan, 253 nurses working in hospitals affiliated with Kashan University of Medical Sciences  were investigated. A non-probability quota sampling method was used. Data were collected using questionnaires on the demographic information of nurses and patients, along with a researcher-made checklist for evaluating the nurses’ clinical Intravenous cannulation skills. Data analysis was performed using SPSS version 26, employing statistical tests such as the independent t-test, analysis of variance (ANOVA), Pearson correlation, and multiple regression.</span></span></span></span><br> <span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong><span style="font-size:10.0pt"><span style="font-family:"Cambria",serif"><span style="color:#44546a">Findings:</span></span></span></strong> <span style="font-size:10.0pt"><span style="font-family:"Cambria",serif">The mean total score for the nurses’ Intravenous cannulation skills was 33.73±8.33, which corresponded to 84.2% of the maximum score (40 points). Over 90% of the nurses rated their Intravenous cannulation skills as good to excellent. The average duration of the cannulation process was 85.4±13.6 minutes. Moreover, the mean Intravenous cannulation skill score for nurses in the emergency department was significantly lower than that in other departments (p<0.05).</span></span></span></span><br> <span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong><span style="font-size:10.0pt"><span style="font-family:"Cambria",serif"><span style="color:#44546a">Conclusion</span></span></span></strong><strong><span style="font-size:10.0pt"><span style="font-family:"Cambria",serif">:</span></span></strong><span style="font-size:10.0pt"><span style="font-family:"Cambria",serif"> About 90% of nurses met Intravenous cannulation standards; targeted training to address gaps could further boost their skills, improve patient outcomes, and cut hospital stays and costs.</span></span></span></span> Clinical Skills,Venipuncture,Nurses,Nursing Education, 89 95 http://jccs.daneshafarand.org/browse.php?a_code=A-10-287-2&slc_lang=en&sid=8 S.M.H. Mousavi 1003194753284600387733 1003194753284600387733 No Medical Surgical Nursing Department, Faculty of Nursing and Midwifery, Kashan University of Medical Sciences, Kashan, Iran M. Hosseinian 1003194753284600387734 1003194753284600387734 No Department of Pediatric Nursing, Faculty of Nursing and Midwifery, Kashan University of Medical Sciences, Kashan, Iran M. Rezaei 1003194753284600387724 1003194753284600387724 Yes Trauma Nursing Research Center, Kashan University of Medical Sciences, Kashan, Iran