fa <strong>Aims</strong>: Several studies have shown controversy over the effectiveness of various educational methods. This study was performed with the aim of comparing the effect of face-to-face education and educational booklet on health-related quality of life in patients suffering from type 2 diabetes.<br> <strong>Materials and Methods: </strong>In this clinical trial study, which was conducted in 2017, 120 patients qualified to enter the study were selected by random sampling; they were randomly allocated to 3 groups, including, face-to-face group, education through booklet, and control group. The data were collected through Diabetes Quality of Life-Brief Clinical Inventory (DQL-BCI). Patients in the two intervention groups were presented with materials with the same educational content, but different teaching methods. The data were analyzed by SPSS 21, using Chi-square, one-way analysis of variance, paired t-test, and Tukey&#39;s post hoc test.<br> <strong>Findings:</strong> Before intervention, mean score of health-related quality of life in patients in the 3 groups was not statistically significant (p=0.1). After intervention, there was a significant difference between the mean score of health-related quality of life of patients in intervention groups and control group (p=0.001). However, there was no significant difference between the patients in face-to-face and education through booklet groups (p>0.05).<br> <strong>Conclusion: </strong>The effect of face-to-face education and educational booklet on health-related quality of life in patients with type 2 diabetes is the same. Face-to-Face Education,Health-Related Quality of Life,Type 2 Diabetes, 75 80 http://jccs.daneshafarand.org/browse.php?a_code=A-10-47-2&slc_lang=fa&sid=8 A.K. Alamdari 1003194753284600387072 1003194753284600387072 No Nursing Department, Nursing Faculty, Yasuj University of Medical Sciences, Yasuj, Iran R. Taheri 1003194753284600387073 1003194753284600387073 No Nursing Department, Nursing Faculty, Yasuj University of Medical Sciences, Yasuj, Iran A. Afrasiabifar 1003194753284600387071 1003194753284600387071 No Nursing Department, Nursing Faculty, Yasuj University of Medical Sciences, Yasuj, Iran M.L. Rastian R115_rastian@yahoo.com 1003194753284600387070 1003194753284600387070 Yes Nursing Department, Nursing Faculty, Yasuj University of Medical Sciences, Yasuj, Iran